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Remember, your curiosity is a gift, and those who value it are worth keeping close. Firstly, the 1/3 Projector profile is known for its investigative nature. As a 1/3 Projector, you have a natural curiosity that drives you to explore and understand the world around you.
Personal Experience as a 1/3 Projector:
A similar process was used to additionally heterodimerize EGFR and HER2 BsAbs with an irrelevant CD33 BsAb. When applied to a chip coated with both EGFR and HER2, the avidity of the EGFRxHER2 T-BsAb improved to levels comparable to the homodimeric T-BsAbs. The journey of a 1/3 Manifestor is one of discovery, growth, and self-realization. It’s about understanding your unique energy and learning how to navigate the world in a way that aligns with who you truly are.
A Closer Look at Human Design Profile 1/3 Investigator Martyr
They can accept and appreciate their unique path by understanding that their journey involves thorough investigation and experiential learning. Each element in a Human Design Chart is interconnected, and understanding these interactions provides a more comprehensive view of one’s design. Human Design, a system that combines astrology, the I Ching, Kabbalah, the Hindu-Brahmin chakra model, and quantum physics, offers an in-depth analysis of the individual personality.
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Managing Your Energy as a Manifestor
Without these solid foundations, you don’t feel prepared enough to use your incredible 3rd line energy of experimenting. In relationships, career, and personal growth, the understanding of your 1/3 Profile can serve as a powerful guide. By aligning your life with your innate design, you can live authentically and fulfill your potential. The combination of the Investigator and Martyr in the 1/3 Profile leads to a life characterized by a deep search for truth, driven by both intellectual curiosity and experiential learning. Individuals with this profile often emerge as experts in their fields due to their exhaustive research and first-hand experiences.
Experienced Human Design Consultants
During this time, the opinion of the Reflector can repeatedly change, as he will change. And if after 29 days you find that a new friend can become your friend or someone closer, then most likely it really is. You are happy to be ready to try something new for yourself, without fear of mistakes. And more often than not, it is with mistakes that you will begin. But the more time you devote to a new activity for yourself, the better you can “penetrate” it. You do not close yourself from the world, hiding in your cozy comfort zone, limiting the circle of friends.
The Interplay of Depth and Experience
Waiting to be recognized and invited is the first step in knowing how to move forward in life. What I like about Human Design is that it’s not a belief system. The founder, Ra, simply said to apply the knowledge that pertains to you and simply see if it works.
Introduction: The Unique Path of the 1/3 Profile
Reflection enables you to extract wisdom from your experiences and apply it in future situations. Be true to your nature, follow your Sacral responses, and embrace your unique journey as a 1/3 Generator. The depth and knowledge you can attain as a 1/3 Generator is truly remarkable.
The Projector Movement Blog
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This openness allows them to mirror their environment and the people in it, hence the term ‘Reflector’. Our thematic website will help you to understand the Human Design System properly at the initial stage and find out all the benefits of this teaching for yourself. Only a system analyst can give you the most correct understanding of your chart. Of course, we don’t know anything about your selection criteria, but you yourself will always be able to realize which person is right for you and which is not. Therefore, do not hesitate to make a mistake and continue searching until you find the right person.
The first number in the 1/3 Profile signifies the Investigator role. Investigators have an innate need to probe the depth of any topic that interests them. They are driven by a need for security, which they obtain by gathering information and understanding their environment on a deep level. The depth of their research and understanding often results in a strong foundation of knowledge.
Investigator Martyrs 1/3 tend to act like Role Model Hermits 6/2s. Essentially, many 1/3s feel that they need to reinvent the wheel and become a role model for others, but that is not what a 1/3 is here to be. You are here to build a foundation and become an expert at it, rather than a role model. By implementing these tips and insights, you can navigate life as a 1/3 Investigator Martyr with greater confidence, self-awareness, and fulfillment. By acknowledging and nurturing these strengths, you can make the most of your 1/3 Investigator Martyr profile and thrive in various aspects of your life.
First, understand that authenticity means staying true to your investigative nature. Allow your curiosity to guide you, and don’t suppress your desire to explore and understand. On the other hand, Generators and Manifesting Generators with the 1/3 Profile could utilize their sustainable energy in deep investigation and experimentation, leading to mastery in their chosen fields. They may feel a strong satisfaction when they’re immersed in exploring their interests and learning from their experiences.
The challenge for the 1/3 profile is to find a balance between their need for depth and the practicalities of everyday life. While their investigative nature is a strength, they must also learn when to let go and accept things at face value. We next investigated how the observed differences between tumor bivalent and tumor monovalent T-BsAbs would translate to efficacy in vivo. As in previous in vivo experiments, EGFRxEGFR, HER2xHER2, and EGFRxHER2 T-BsAb reduced SW1990 tumor growth, although only HER2xHER2 and EGFRxHER2 significantly prolonged survival (Fig. 5C). Strikingly, neither of the tumor monovalent T-BsAbs (EGFRxCD33 and HER2xCD33) demonstrated any benefit over ‘T cells only’ or CD33xCD33-treated control groups. EGFR and HER2 were useful targets for driving T cell infiltration and tumor ablation.
Surround yourself with people who appreciate and respect your investigative nature. Lastly, your life theme is “Frustration,” but it’s essential to understand this isn’t a negative thing. It’s a signpost that you’re off track, guiding you back to living in alignment with your design. With regards to profiles, I thought it would make an interesting project to see how they compare with the Myers-Briggs types, and whether there’s any obvious overlap. Bear in mind there are 12 different profiles in Human Design and 16 identified by the Myers-Briggs personality test1. When Projectors have faith in all aspects of their design and embrace their strategy, they will notice that people are drawn to their expertise and authority in a subject, and their lives become far easier.
SPR analysis revealed significant reductions in avidity between EGFRxEGFR and EGFRxCD33 (∼150-fold) and between HER2xHER2 and HER2xCD33 (∼6000-fold) (Table 3). Interestingly, in both FACS and ADTC analyses, the EGFRxHER2 heterodimer achieved EC50s similar to those of bivalent EGFRxEGFR T-BsAbs, which was the most effective T-BsAb in both in vitro assays. Pancreatic cancers are known for being one of the most ‘stroma rich’ tumors. The majority of PDAC tumors are comprised of stromal cells such as fibroblasts and myeloid cells [41]. Myeloid-depleting antibodies were combined with EGFR T-BsAb treatment (Supp. Figure 4A).
This can help them feel seen, understood, and less alone in their journey. Reflectors make up a small percentage of the human population, and being a 1/3 Reflector is an even rarer experience. In Human Design, the Reflector type is unique in its open centers, enabling them to reflect the world around them.
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